C5-benzyl SAHA
CAS No. 2115700-64-4
C5-benzyl SAHA ( —— )
产品货号. M13367 CAS No. 2115700-64-4
C5-benzyl SAHA is a C5-modified SAHA analog that displays dual selectivity to HDAC.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
100MG | 获取报价 | 有现货 |
|
200MG | 获取报价 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称C5-benzyl SAHA
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述C5-benzyl SAHA is a C5-modified SAHA analog that displays dual selectivity to HDAC.
-
产品描述C5-benzyl SAHA is a C5-modified SAHA analog that displays dual selectivity to HDAC6 (IC50=0.27 uM) and HDAC8 (IC50=0.38 uM) over HDAC 1, 2, and 3 (IC50=2.9-5.8 uM); dose dependently and selectively increases in levels of acetyl-α-tubulin in U937 leukemia cells.
-
同义词——
-
通路Cell Cycle/DNA Damage
-
靶点HDAC
-
受体HDAC
-
研究领域——
-
适应症——
化学信息
-
CAS Number2115700-64-4
-
分子量354.45
-
分子式C21H26N2O3
-
纯度>98% (HPLC)
-
溶解度——
-
SMILES——
-
化学全称4-benzyl-N8-hydroxy-N1-phenyloctanediamide
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Negmeldin AT, et al. Bioorg Med Chem Lett. 2017 Aug 1;27(15):3254-3258.
产品手册
关联产品
-
NCC-149
A potent and selective HDAC8 inhibitor with IC50 of 70 nM.
-
Remetinostat
Remetinostat is a hydroxamic acid-based inhibitor of histone deacetylase enzymes.
-
Cedryl acetate
The fungal transformation of cedryl acetate was investigated for the first time by using Cunninghamella elegans.